Publications
Recent publications from members of our department are shown below. View a full list of publications on Pubmed
INTRODUCTION: Parent-Child Interaction Therapy (PCIT) is a strongly evidence-based treatment (EBT) for disruptive behaviors in young children. However, PCIT research with Black families has identified…
December 25th, 2025
OBJECTIVE: The pharmacological treatment of temporal lobe epilepsy (TLE), a disorder characterized by recurrent seizures and cognitive dysfunction, is limited to symptomatic control. Identifying novel…
December 22nd, 2025
The ability to associate environmental stimuli with positive outcomes is a fundamental form of learning. While extensive research has focused on midbrain dopamine neurons during associative learning, …
December 9th, 2025
Cocaine and Morphine Converge to Disrupt Chloride Homeostasis in Ventral Tegmental Area GABA Neurons
Identifying shared neural mechanisms influenced by diverse classes of drugs of abuse is essential for understanding addiction and for developing broad-spectrum treatments for substance use disorders. …
December 5th, 2025
Hyaluronan and proteoglycan link protein 2 (HAPLN2) / Brain link protein-1 (Bral1) is important for the binding of chondroitin sulfate proteoglycans (CSPGs) to hyaluronan and thus for the formation of…
November 26th, 2025
Extra-ciliary role for polycystins in regulation of Ezrin and renal tubular morphology
Full understanding of the functions of the polycystin proteins, PC1 and PC2, in renal epithelial cells is obscured by signaling complexity and renal injury that occurs in Autosomal Dominant Polycystic…
November 24th, 2025
The genetically epilepsy-prone rat (GEPR) is a long-standing animal model for inherited epilepsy, with seizures triggered by high-intensity acoustic stimulation (audiogenic seizures), leading to gener…
November 17th, 2025
CONCLUSIONS: Female Syrian hamsters exhibit heightened vulnerability to Ang II-induced hypertension and renal damage compared to males, marked by exaggerated blood pressure elevation, enhanced renal i…
November 4th, 2025
OBJECTIVE: For over four decades, the substantia nigra pars reticulata (SNr) has been recognized as a critical structure in the modulation of seizure activity. Pharmacological and optogenetic inhibiti…
November 3rd, 2025
CONCLUSIONS: β-Nic slows Nic clearance in rats and enhances and prolongs the discriminative stimulus effects of Nic, suggesting it may contribute to the abuse liability of ENDS.…
November 2nd, 2025
Serotonin transporter: a potential new immune checkpoint for cytotoxic T cells
No abstract…
October 29th, 2025
Oxidized angiotensin II peptides as mediators of cell signaling?
Both reactive oxygen species (ROS) and angiotensin II (Ang II) play important roles in the pathogenesis of various diseases. Since Ang II was found to activates NADPH oxidase to produce ROS, many labo…
October 23rd, 2025
Cerebral amyloid angiopathy: a narrative review
Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder characterized by the accumulation of amyloid-beta (Aβ) in the walls of cerebral vessels. It is commonly associated with cognitive decli…
October 2nd, 2025
In people with HIV (PWH), T cell immune activation and endothelial inflammation are contributors of the increased cardiovascular risk, however the mechanisms remain poorly understood. PAR1 connects th…
October 1st, 2025
Background: Immunotherapy has revolutionized oncology care, but clinical response to immune checkpoint inhibitors (ICIs) remains unpredictable, and treatment carries substantial risks and costs. The E…
September 13th, 2025
A Journey between Neurons and Astrocytes: A Tribute to Giorgio Carmignoto
The intimate relation between astrocytes and blood vessels was proposed by Camillo Golgi in 1870. Santiago Ramon y Cajal subsequently introduced the idea of astrocytes as regulators of functional hype…
September 4th, 2025
Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics
O-linked β-N-acetylglucosamine (O-GlcNAc) modification (i.e., O-GlcNAcylation) on proteins is an essential modification in physiology and pathology. Although O-GlcNAcylation is functionally critical,…
August 30th, 2025
Cocaine and Morphine Converge to Disrupt Chloride Homeostasis in Ventral Tegmental Area GABA Neurons
Identifying shared neural mechanisms influenced by diverse classes of drugs of abuse is essential for understanding addiction and for developing broad-spectrum treatments for substance use disorders. …
August 8th, 2025
Enhanced beta power emerges from simulated parkinsonian primary motor cortex
Primary motor cortex (M1) layer 5B pyramidal tract (PT5B) neurons develop intrinsic pathology in rodent and primate Parkinson’s disease (PD) models. We used computer simulation to predict how decrease…
August 5th, 2025
Subsecond Analysis of Locomotor Activity in Parkinsonian Mice
The degeneration of midbrain dopamine (DA) neurons disrupts the neural control of natural behavior, such as walking, posture, and gait in Parkinson’s disease. While some aspects of motor symptoms can …
July 28th, 2025