Publications
Recent publications from members of our department are shown below. View a full list of publications on Pubmed
NAD+ prevents chronic kidney disease by activating renal tubular metabolism
Chronic kidney disease (CKD) is associated with renal metabolic disturbances, including impaired fatty acid oxidation (FAO). Nicotinamide adenine dinucleotide (NAD+) is a small molecule that participa…
March 10th, 2025
Phosphorylation of NLGN4X Regulates Spinogenesis and Synaptic Function
Neuroligins (NLGNs) are a family of postsynaptic adhesion molecules that bind to their presynaptic partners, neurexins, facilitating the formation and maintenance of synapses. In humans, there are fiv…
March 3rd, 2025
The melanocortin receptors are a class of centrally and peripherally expressed G protein-coupled receptors, of which the MC3R and MC4R subtypes are implicated in the regulation of appetite and energy …
January 20th, 2025
Motor cortical neuronal hyperexcitability associated with α-synuclein aggregation
ΑBSTRACT: In Parkinson’s disease (PD), Lewy pathology deposits in the cerebral cortex, but how the pathology disrupts cortical circuit integrity and function remains poorly understood. To begin to ad…
January 14th, 2025
Sub-second characterization of locomotor activities of mouse models of Parkinsonism
The degeneration of midbrain dopamine (DA) neurons disrupts the neural control of natural behavior, such as walking, posture, and gait in Parkinson’s disease. While some aspects of motor symptoms can …
January 7th, 2025
Aging affects virtually all organs of the body, but perhaps it has the most profound effects on the brain and its neurotransmitter systems, which influence a wide range of crucial functions, such as a…
December 10th, 2024
Piriform cortex is an ictogenic trigger zone in the primate brain
OBJECTIVE: Area tempestas, a functionally defined region in the anterior piriform cortex, was identified as a crucial ictogenic trigger zone in the rat brain in the 1980s. However, whether the primate…
December 5th, 2024
Progressive noradrenergic degeneration and motor cortical dysfunction in Parkinson's disease
The locus coeruleus norepinephrine (LC-NE) system plays an important role in regulating brain function, and its neuronal loss has been well-documented in Parkinson’s disease (PD). The LC-NE neurodegen…
November 26th, 2024
VICR: A novel software for unbiased video and image analysis in scientific research
In scientific research, objectivity and unbiased data analysis is crucial for the validity and reproducibility of outcomes. This is particularly important for studies involving video or image categori…
October 24th, 2024