Dr. Vicini’s research focuses on GABA and glutamate ligand-gated channels at the inhibitory and excitatory synapses relevant to the understanding of mechanisms of synaptic plasticity and the plasticity of disease . He utilizes many techniques and animal models. This includes classical slice electrophysiology, calcium imaging, immunhistochemistry, and behavior. Dr. Vicini has focused on GABAergic and glutamatergic neurons in various brain area including brainstem, cortex and hippocampus. The main projects currently in the lab currently are GABAergic connectivity within the dorsovagal complex, synaptic plasticity deficits in alzheimer’s disease, sharp wave ripples and perineuronal nets, microglia morphology and motility, alterations of synaptic plasticity after neonatal anticonvulsant exposure, and synaptic adaptations consequent to high-frequency head impacts
Academic Appointment(s)
- Primary
- Professor, Pharmacology & Physiology
- Secondary
- Professor, Neuroscience