Publications
Recent publications from members of our department are shown below. View a full list of publications on Pubmed
Mass spectrometry identifies tau C-terminal phosphorylation cluster during neuronal hyperexcitation
Tau is a microtubule-associated protein implicated in Alzheimer’s disease (AD) and other neurodegenerative disorders termed tauopathies. Pathological, aggregated forms of tau form neurofibrillary tang…
September 23rd, 2024
Sex-dependent regulation of retinal pigment epithelium and retinal function by <em>Pgc-1α</em>
Age-related macular degeneration (AMD) is a major cause of blindness that affects people over 60. While aging is the prominent factor in AMD, studies have reported a higher prevalence of AMD in women …
September 17th, 2024
Motor Cortical Neuronal Hyperexcitability Associated with α-Synuclein Aggregation
Dysfunction of the cerebral cortex is thought to underlie motor and cognitive impairments in Parkinson disease (PD). While cortical function is known to be suppressed by abnormal basal ganglia output …
September 16th, 2024
Motor Cortical Neuronal Hyperexcitability Associated with α-Synuclein Aggregation
Dysfunction of the cerebral cortex is thought to underlie motor and cognitive impairments in Parkinson disease (PD). While cortical function is known to be suppressed by abnormal basal ganglia output …
August 2nd, 2024
Firing Patterns of Mitral Cells and Their Transformation in the Main Olfactory Bulb
Mitral cells (MCs) in the main olfactory bulb relay odor information to higher-order olfactory centers by encoding the information in the form of action potentials. The firing patterns of these cells …
July 27th, 2024
Dysfunction of motor cortices in Parkinson's disease
The cerebral cortex has long been thought to be involved in the pathophysiology of motor symptoms of Parkinson’s disease. The impaired cortical function is believed to be a direct and immediate effect…
July 27th, 2024
Increased vulnerability to seizures in aging has been well documented both clinically and in various models of aging in epilepsy. Seizures can exacerbate cognitive decline that is already prominent in…
July 20th, 2024
VICR: A Novel Software for Unbiased Video and Image Analysis in Scientific Research
In scientific research, objectivity and unbiased data analysis is crucial for the validity and reproducibility of outcomes. This is particularly important for studies involving video or image categori…
July 9th, 2024
Decreased excitability of pyramidal tract neurons in layer 5B (PT5B) of primary motor cortex (M1) has recently been shown in a dopamine-depleted mouse model of parkinsonism. We hypothesized that decre…
July 1st, 2024