Publications
Recent publications from members of our department are shown below. View a full list of publications on Pubmed
Enhanced beta power emerges from simulated parkinsonian primary motor cortex
Primary motor cortex (M1) layer 5B pyramidal tract (PT5B) neurons develop intrinsic pathology in rodent and primate Parkinson’s disease (PD) models. We used computer simulation to predict how decrease…
August 5th, 2025
The Renin-Angiotensin System Modulates SARS-CoV-2 Entry via ACE2 Receptor
The renin-angiotensin system (RAS) plays a central role in cardiovascular regulation and has gained prominence in the pathogenesis of Coronavirus Disease 2019 (COVID-19) due to the critical function o…
July 30th, 2025
Subsecond Analysis of Locomotor Activity in Parkinsonian Mice
The degeneration of midbrain dopamine (DA) neurons disrupts the neural control of natural behavior, such as walking, posture, and gait in Parkinson’s disease. While some aspects of motor symptoms can …
July 28th, 2025
Tracking conditioned fear in pair-housed mice using deep learning and real-time cue delivery
Post-traumatic stress disorder (PTSD) is a complex and prevalent neuropsychiatric condition that arises in response to exposure to a traumatic event. A common diagnostic criterion for PTSD includes he…
July 18th, 2025
EpiSwitch PSE Blood Test Reduces Unnecessary Prostate Biopsies: A Real-World Clinical Utility Study
Background/Objectives: Prostate cancer (PCa) remains a major contributor to cancer-related morbidity and mortality worldwide. Current diagnostic strategies, largely based on PSA screening, lack specif…
July 12th, 2025
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus responsible for Coronavirus Disease 2019 (COVID-19), utilizes its spike protein to infect host cells. In addition to angiotensin…
July 12th, 2025
Triglyceride metabolism controls inflammation and microglial phenotypes associated with APOE4
Changes to cellular lipids accompany shifts in microglial cell state, but the functional significance of these metabolic changes remains poorly understood. In human induced pluripotent stem cell-deriv…
July 11th, 2025
CONCLUSIONS: CAA did not significantly dysregulate AT(1)R levels in the brains of Tg-SwDI mice compared to wild-type mice. Drug treatment caused no significant brain AT(1)R alterations. Further studie…
June 6th, 2025
Arteries are finely tuned thermosensors regulating myogenic tone and blood flow
In response to changing blood pressure, arteries adjust their caliber to control blood flow. This vital autoregulatory property, termed vascular myogenic tone, stabilizes downstream capillary pressure…
May 20th, 2025