Publications
Recent publications from members of our department are shown below. View a full list of publications on Pubmed
Fractal dimension (FD) is a widely recognized metric in mathematics and physics for quantifying the complexity of intricate objects and processes. In this study, we propose novel algorithms to estimat…
April 15th, 2025
Optogenetic stimulation of the dorsal striatum bidirectionally controls seizures
Despite a century of development of antiseizure medications, up to a third of people with epilepsy do not achieve seizure freedom with drug therapy. Deep brain stimulation is of growing use, but just …
March 31st, 2025
Rising Trends in Prostate Cancer Among Asian Men: Global Concerns and Diagnostic Solutions
Asia comprises 60% of the global male population, yet Asian men’s health issues, such as prostate cancer, remain sparse in the literature. Clinical researchers have often overlooked prostate cancer in…
March 28th, 2025
NAD+ prevents chronic kidney disease by activating renal tubular metabolism
Chronic kidney disease (CKD) is associated with renal metabolic disturbances, including impaired fatty acid oxidation (FAO). Nicotinamide adenine dinucleotide (NAD+) is a small molecule that participa…
March 10th, 2025
Phosphorylation of NLGN4X Regulates Spinogenesis and Synaptic Function
Neuroligins (NLGNs) are a family of postsynaptic adhesion molecules that bind to their presynaptic partners, neurexins, facilitating the formation and maintenance of synapses. In humans, there are fiv…
March 3rd, 2025
The melanocortin receptors are a class of centrally and peripherally expressed G protein-coupled receptors, of which the MC3R and MC4R subtypes are implicated in the regulation of appetite and energy …
January 20th, 2025
Motor cortical neuronal hyperexcitability associated with α-synuclein aggregation
ΑBSTRACT: In Parkinson’s disease (PD), Lewy pathology deposits in the cerebral cortex, but how the pathology disrupts cortical circuit integrity and function remains poorly understood. To begin to ad…
January 14th, 2025
Sub-second characterization of locomotor activities of mouse models of Parkinsonism
The degeneration of midbrain dopamine (DA) neurons disrupts the neural control of natural behavior, such as walking, posture, and gait in Parkinson’s disease. While some aspects of motor symptoms can …
January 7th, 2025
Aging affects virtually all organs of the body, but perhaps it has the most profound effects on the brain and its neurotransmitter systems, which influence a wide range of crucial functions, such as a…
December 10th, 2024