Welcome to the Department of Pharmacology & Physiology at Georgetown University.
The diverse research programs of our faculty focus on cellular communication and signal transduction.
Our department offers graduate programs leading to both the Ph.D. and M.S. degrees. Please explore our website.
- Ken Dretchen, Chair
Because research is such an important aspect of our programs, we include links to recent faculty publications - Click each title to see the abstracts
Mechanism of protein decarbonylation. Free Radic Biol Med. 2013 Sep 14;65C:1126-1133. [Epub]
IL-22 activates oxidant signaling in pulmonary vascular smooth muscle cells. Cell Signal. 2013 Sep 7;25(12):2727-2733.[Epub]
Dopamine D2 Receptors Regulate Collateral Inhibition between Striatal Medium Spiny Neurons. J Neurosci. 2013 Aug 28;33(35):14075-86
CCL5 and cytokine expression in the rat brain: Differential modulation by chronic morphine and morphine withdrawal. Brain Behav Immun. 2013 Aug 19. [Epub]
The role of antioxidants in the era of cardio-oncology. Cancer Chemother Pharmacol. 2013 Aug 20. [Epub]
Chemistry and pharmacological studies of 3-alkoxy-2,5-disubstituted-pyridinyl compounds as novel selective alpha4beta2 nicotinic acetylcholine receptor ligands that reduce alcohol intake in rats. J Med Chem. Epub, Apr, 2013
Transient receptor potential channels and energy homeostasis. Trends Endocrin Metab. Epub, July, 2013
Distinct roles for somatically and dendritically synthesized brain-derived neurotrophic factor in morphogenesis of dendritic spines. J Neurosci. Epub, July, 2013
The skinny on brain-derived neurotrophic factor: evidence from animal models to GWAS, J Mol Med Epub, July 5 , 2013
Molecular and neural bases underlying roles of BDNF in the control of body weight, Front. Neurosci. 7:Art37, 2013
Two newly identified exons in human GRM1 express a novel splice variant of metabotropic glutamate 1 receptor, Gene 519:367-373, 2013
Differential effects of serotonin-specific and excitotoxic lesions of OFC on conditioned reinforcer devaluation and extinction in rats, Behav. Brain Res. 246:10-14, 2013
Midbrain-derived neurotrophins support survival of immature striatal projection neurons, J Neurosci 33:3363-3369, 2013
Mossy fiber-CA3 synapses mediate homeostatic plasticity in mature hippocampal neurons, Neuron 77:99-114. 2013
Defense-like behaviors evoked by pharmacological disinhibition of the superior colliculus in the primate, J Neurosci 33:150-155, 2013
Direct and GABA-mediated indirect effects of nicotinic ACh receptor agonists on striatal neurones, J Physiol. 2013 591:203-217, 2013