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Welcome to the Department of Pharmacology & Physiology at Georgetown University. The diverse research programs of our faculty focus on cellular communication and signal transduction. Our department offers graduate programs leading to both the Ph.D. and M.S. degrees. Please explore our website.
            
- Ken Dretchen, Chair

Recent faculty publications - Click each title to see the abstracts

Proposed role of primary protein carbonylation in cell signaling. Redox Rep. 17:90-94, 2012

Dendritic BDNF synthesis is required for late-phase spine maturation and recovery of cortical responses following sensory deprivation. J Neurosci 32:4790, 2012

Oxidant signaling for interleukin-13 gene expression in lung smooth muscle cells. Free Radic. Biol. Med. 52:1552, 2012

Anticonvulsant effect of retigabine during postnatal development in rats. Epilepsy Res Apr 5,2012 epub

Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin. Nature Medicine 18:564, 2012

Effects of sazetidine-A, a selective alpha4beta2* desensitizing agent, on body temperature regulation in mice and rats. Eur J Pharmacol Feb 2012

Assessing the effects of chronic sazetidine-A on nicotine self-administration in both male and female rats. Psychopharmacol. Feb 2012

Neonatal exposure to phenobarbital potentiates schizophrenia-like behavioral outcomes in the rat. Neuropharmacology Feb 2012

Identification and functional characterization of polo-like kinase 2 autoregulatory sites. Neuroscience Jan 2012

Ventral pallidum mediates amygdala-evoked deficits in prepulse inhibition. Behavioral Neuroscience Jan 2012

Effects of neonatal antiepileptic exposure on cognitive, emotional, and motor function in adult rats. J. Pharmacol. Exp. Ther. Mar 2012